We developed computational tools to facilitate nanobody discovery and engineering.
Llamanade for nanobody humanization
Based on big data analysis, we developed "Llamanade," an open-source software to facilitate the rational humanization of camelid nanobodies. Using sequence as input, Llamanade can rapidly extract sequence features, model structures, and optimize solutions to humanize nanobodies.
Web server available at: http://www.llamande.app